RecruitingNot ApplicableNCT05708443

Effect of Combined Endurance Training on ADL and Walking in COPD Patients

Effect of Combined Upper and Lower Extremity Endurance Training Versus Lower Extremity Training Alone on ADL and Walking in COPD Patients

Sponsor

Istituti Clinici Scientifici Maugeri SpA

Enrollment

36 participants

Start Date

Jan 10, 2023

Study Type

INTERVENTIONAL

Conditions

COPD

Summary

Chronic Obstructive Pulmonary Disease (COPD) is a chronic disease with related exercise intolerance and marked disability due to symptoms such as dyspnea and fatigue. Effort intolerance and exercise-induced symptoms cause marked impairment in completing activities of daily living (ADL). Pulmonary rehabilitation (PR), which has exercise as a major component, is considered a key treatment in the management of COPD since PR is effective in improving exercise tolerance, exercise-induced dyspnea and fatigue, and health-related quality of life. Rehabilitation is also effective in improving the time required to perform ADLs, reducing symptoms and disability. Studies show that rehabilitation protocols with upper limb exercises added to lower limb training are able to give additional benefits in terms of effort tolerance (endurance time at the arm ergometer and oxygen consumption) and reduction of dyspnea at iso-load. The primary aim of this study is to evaluate whether the combined "arm and leg" training modality, compared to a gold standard protocol -involving only the lower limbs training- is more effective in improving ADL performance in terms of reduction of exercise time for a specific test (GLITTRE test).

Eligibility

Plain Language Summary

Simplified for easier understanding

This study is looking at whether a combined exercise training program can improve the ability of people with moderate-to-severe COPD (chronic obstructive pulmonary disease) to carry out daily activities and walk more easily. **You may be eligible if...** - You have COPD classified as moderate to severe (GOLD stage 2-3) - Your lung function tests show a specific range of airflow limitation - You are able to walk and climb stairs without help - Your condition is currently stable **You may NOT be eligible if...** - You require continuous supplemental oxygen - You have serious bone, nerve, or heart problems that would prevent safe exercise - You have significant cognitive impairment - You had a recent flare-up of COPD in the past 15 days requiring a change in treatment - You have another lung disease besides COPD - You are in the terminal stage of illness Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERLL group

The program will include daily sessions of 90 minutes, for a total of 14 sessions, consisting of: 1. 60 minutes on a stationary bike for the lower limbs (2 sessions per day of 30 minutes) at moderate-high intensity; 2. 30 minutes of strengthening exercises for upper limbs (biceps, pectoral, latissimus dorsi) and lower limbs (quadriceps, gluteus and hamstrings) performed free body or with the aid of weights. All sessions will be supervised by a physiotherapist.

OTHERL+UL group

These patients will attend a rehabilitation program with daily sessions of 90 minutes, for a total of 14 sessions, consisting of: 1. 30 minutes on a stationary bike for the lower limbs (1 session of 30 minutes per day) at moderate-high intensity; 2. 30 minutes with arm-ergometer (1 daily session of 30 minutes) at moderate-high intensity; 3. 30 minutes of strengthening exercises for upper limbs (biceps, pectoral, latissimus dorsi) and lower limbs (quadriceps, gluteus and hamstrings) performed free body or with the aid of weights. All sessions will be supervised by a physiotherapist.