RecruitingNCT05714618

MR Evidence of Cardiac Inflammation Post-Stroke

Magnetic Resonance Imaging Evidence of Cardiac Inflammation Post-Stroke


Sponsor

Luciano A. Sposato

Enrollment

44 participants

Start Date

Oct 1, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

The present study is an investigator initiated, single-centre, prospective, proof-of-concept cohort study aiming to enroll 44 patients with acute middle cerebral artery (MCA) ischemic stroke, involving the right (n=22) and left (n=22) MCA territories and 24 control patients with acute focal neurological symptoms but no evidence of acute brain infarct on DWI-MRI.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying B Natriuretic Peptide, Gadolinium-enhanced cardiac MRI, and others for people with inflammation, myocardial injury, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTGadolinium-enhanced cardiac MRI

Cardiac magnetic resonance imaging (MRI) with a protocol designed to measure myocardial inflammation and fibrosis.

DIAGNOSTIC_TESTB Natriuretic Peptide

Measurement of B Natriuretic Peptide on patients' blood samples at 10 and 60+/-15 days.

DIAGNOSTIC_TESTSystemic inflammatory markers

Measurement of a panel of 92 systemic inflammatory markers on patients' blood samples at 10 and 60+/-15 days.


Locations(1)

Heart & Brain Lab, Western University

London, Ontario, Canada

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NCT05714618


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