Inflammation Clinical Trials

273 recruitingLast updated: July 17, 2026

There are 273 actively recruiting inflammation clinical trials across 58 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1, Early Phase 1. Top locations include Boston, Massachusetts, United States, New York, New York, United States, Montreal, Quebec, Canada. Updated daily from ClinicalTrials.gov.


Inflammation Trials at a Glance

273 actively recruiting trials for inflammation are listed on ClinicalTrialsFinder across 6 cities in 58 countries. The largest study group is Not Applicable with 122 trials, with the heaviest enrollment activity in Boston, New York, and Montreal. Lead sponsors running inflammation studies include Massachusetts General Hospital, University of Aarhus, and Queen Mary University of London.

Browse inflammation trials by phase

Treatments under study

About Inflammation Clinical Trials

Looking for clinical trials for Inflammation? There are currently 208 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Inflammation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Inflammation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 273 trials

Recruiting

Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions

ArthritisStill's Disease, Adult-OnsetSystemic Inflammation+1 more
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)2,000 enrolled1 locationNCT03510442
Recruiting

Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics

Genetic diseasesFeverROSAH+4 more
National Human Genome Research Institute (NHGRI)5,000 enrolled5 locationsNCT00001373
Recruiting

NIAID Centralized Sequencing Protocol

autoimmunityPrimary ImmunodeficiencyAtopy+1 more
National Institute of Allergy and Infectious Diseases (NIAID)20,000 enrolled2 locationsNCT03206099
Recruiting

Natural History of the Human Biological Response to Environmental Exposure and Injury

Metabolic DiseaseInflammationNormal Controls
National Institute of Environmental Health Sciences (NIEHS)2,000 enrolled1 locationNCT04888923
Recruiting
Phase 4

Secukinumab Open Label Roll-over Extension Protocol

Autoimmunity, Inflammation
Novartis Pharmaceuticals1,000 enrolled167 locationsNCT04638647
Recruiting
Phase 2

A Study to Learn About the Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Late Isolated Microvascular Inflammation

Microvascular Inflammation
Biogen81 enrolled39 locationsNCT07219043
Recruiting

Clinical Safety Guidelines for Managing Distal Shoe Complications

Premature loss of primary molarsSpace MaintainerSoft Tissue Inflammation
University of Florida50 enrolled2 locationsNCT07410442
Recruiting
Not Applicable

Hyaluronic Acid and Polynucleotides for Supra-bony Defects

periodontal inflammationWound HealPeriodontal Diseases+2 more
Queen Mary University of London24 enrolled2 locationsNCT06309719
Recruiting
Not Applicable

PRF as Adjunct to Subgingival Instrumentation in Step 2 Periodontal Therapy

periodontal inflammationPeriodontitisPeriodontal Attachment Loss
University of Bern20 enrolled1 locationNCT07013682
Recruiting

Natural History of Inflammatory Muscle Diseases

Inflammation In Skeletal Muscle
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)500 enrolled1 locationNCT05738824
Recruiting

Diagnosis and Management of Inflammatory and Infectious Diseases

InflammationInfection
National Institute of Allergy and Infectious Diseases (NIAID)400 enrolled1 locationNCT00557726
Recruiting
Phase 4

Colchicine's Effect on Inflammatory Markers

ColchicinePost-operative Atrial FibrillationInflammation in Cardiac Surgery+2 more
Ayesha Ather24 enrolled1 locationNCT07287345
Recruiting
Not Applicable

Heart Analysis in GATED-PET in Patients Having a Gallium-68-DOTATOC PET/CT Exam for Oncology Indication

Cardiac Inflammation
Central Hospital, Nancy, France99 enrolled1 locationNCT06467968
Recruiting
Not Applicable

Independent and Combined Effects of Short-term Sulforaphane Supplementation and Exercise on Immunometabolism in Healthy Adults

InflammationImmunometabolismMitochondrial Function, Bioenergetics
University of British Columbia20 enrolled1 locationNCT07668596
Recruiting
Phase 3

Study on Ketorolac for Improving Outcomes and Prognosis in Patients With Stanford Type A Aortic Dissection

InflammationAortic Dissection
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School360 enrolled1 locationNCT06968806
Recruiting
Phase 2

Effects of IL-1 Beta Inhibition on Vascular Inflammation in TET2 Clonal Hematopoiesis

ASCVDVascular InflammationASCVD Management
Massachusetts General Hospital120 enrolled1 locationNCT06691217
Recruiting
Not Applicable

Ketone Ester And Salt (KEAS) in Older Adults

HypertensionBlood PressureInflammation+2 more
Indiana University35 enrolled1 locationNCT06868719
Recruiting

Immune Cell Response to Stimuli

Inflammation
National Institute of Environmental Health Sciences (NIEHS)750 enrolled1 locationNCT00397280
Recruiting

Inflammation in Clear Aligners With and Without Attachments

periodontal inflammation
University of Nebraska30 enrolled1 locationNCT07506993
Recruiting

Molecular Mechanisms Associated With Breast Implant Complications

Breast Implant; ComplicationsInfection or Inflammation
Indiana University1,000 enrolled3 locationsNCT05736354