RecruitingNot ApplicableNCT05715047

Intervention for Fatigue in HCT Recipients

Reducing Persistent Fatigue Following Hematopoietic Stem Cell Transplantation


Sponsor

Massachusetts General Hospital

Enrollment

66 participants

Start Date

Nov 29, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to assess whether a cognitive-behavioral therapy (CBT) for fatigue intervention is acceptable, feasible, and effective at managing fatigue and improving quality of life for patients following hematopoietic stem cell transplant (HCT).


Eligibility

Min Age: 18 Years

Inclusion Criteria7

  • adult patients (≥ 18 years)
  • have the ability to speak and read English
  • have undergone autologous or allogeneic transplant > 6 months prior to enrollment
  • no evidence of disease relapse requiring therapy
  • no new other malignancy requiring therapy after transplant
  • report moderate to severe fatigue in the past week (FSI average severity item rating ≥ 4 of 0-10)
  • are currently receiving their care at the MGH Blood and Marrow Transplant Clinic

Exclusion Criteria4

  • Patients with active cognitive impairment or uncontrolled psychiatric illness such as schizophrenia that the treating clinician believes prohibits informed consent or participation in the intervention
  • Patients already receiving CBT care
  • Patients living with untreated sleep apnea
  • Patients with hypoxemia requiring oxygen supplementation

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Interventions

BEHAVIORALCBT for Fatigue

10, individualized counseling sessions with a behavioral health counselor via Zoom platform.

BEHAVIORALUsual Care

Standard transplant care.


Locations(1)

Massachusetts General Hospital Cancer Center

Boston, Massachusetts, United States

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NCT05715047


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