RecruitingNot ApplicableNCT06676852

Feasibility and Acceptability of Primary Palliative Care Intervention in Patients Undergoing Hematopoietic Stem Cell Transplantation


Sponsor

Massachusetts General Hospital

Enrollment

40 participants

Start Date

Jan 5, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Primary PC - or training HCT clinicians to deliver PC domains as part of routine practice - is an alternative model of supportive care. We have developed Sentinel, a primary PC intervention for HCT clinicians and patients. This study will assess Sentinel's feasibility and acceptability.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Age 18 years or older
  • Undergoing autologous or allogeneic HCT at MGH

Exclusion Criteria3

  • Prior receipt of inpatient specialty palliative care on two prior admissions in the past 6 months.
  • Significant uncontrolled psychiatric disorders (psychotic disorder, bipolar disorder, major depression) or other co-morbid disease (dementia, cognitive impairment), which the primary oncologist believes prohibits informed consent or ability to participate in study procedures
  • Inability to comprehend English as this is a preliminary/pilot study

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Interventions

BEHAVIORALPrimary palliative care

Enrolled patient participants will receive Sentinel prior to and during their hospitalization for HCT. Prior to HCT, a transplant clinician (nurse practitioner - NP) will conduct a focused PC visit to build rapport, manage expectations regarding HCT, review anticipated symptoms, and discuss illness coping strategies. During the HCT hospitalization, HCT physicians and advanced practice providers will incorporate PC domains into their routine care of patients undergoing HCT.


Locations(1)

Massachusetts General Hospital

Boston, Massachusetts, United States

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NCT06676852


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