RecruitingNot ApplicableNCT05715086
UPURS Trial for Patient-centered Management of Symptomatic Obstructing Stones
Upfront vs Postponed Ureteroscopy (UPURS) Trial for Patient-centered Management of Symptomatic Obstructing Stones
Sponsor
University of California, San Francisco
Enrollment
100 participants
Start Date
Aug 23, 2023
Study Type
INTERVENTIONAL
Conditions
Summary
A prospective, non-blinded, randomized controlled trial studying the management of symptomatic ureteral stones. This study will compare upfront ureteroscopy vs observation and delayed intervention for patients presenting to the emergency department with a symptomatic ureteral stone.
Eligibility
Min Age: 18 Years
Inclusion Criteria4
- Presenting to the Emergency Department (ED)
- Adult (\> 18 yo)
- ≥5mm ureteral stone diagnosed on CT scan
- Presence of symptoms (pain, nausea, vomiting, hematuria)
Exclusion Criteria7
- Strict indication for stent
- Stone burden not amenable to Ureteroscopy (URS)
- Dirty urine analysis (UA) or positive urine culture (UCx)
- Transplant kidney
- Presence of conduit
- Comorbidities not optimized for surgery
- Strong preference for surgery or observation
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Interventions
PROCEDUREUreteroscopy
Upfront ureteroscopy
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05715086