RecruitingNot ApplicableNCT06346483

Ureteroscopy With High-powered Holmium:Yag Laser Lithotripsy With and Moses On or Moses Off

Comparison of Ureteroscopy With High-powered Holmium:Yag Laser Lithotripsy With and Without Moses 2.0 Pulse Modulation


Sponsor

Northwestern University

Enrollment

150 participants

Start Date

Jun 9, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to compare Moses 2.0 pulse modulation technology and the standard high powered Holmium Laser lithotripsy and how it will affect time in the operating room, time using the laser, laser energy, and stone free rates. Currently Moses 2.0 laser technology is FDA approved and currently used in practice since 2021. No study to this date has compared Moses 2.0 without pulse modulation laser technology to Moses 2.0 with pulse modulation laser technology. The study will be including kidney and ureteral stones (a kidney stone located in the tube between the kidney and the bladder) that are 6mm and greater, but less than 20 mm in size undergoing ureteroscopic treatment. High powered lasers are used for "dusting". Dusting is when a laser is used to break a stone down into tiny fragments that are able to pass through the urine.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Inclusion Criteria3

  • Undergoing ureteroscopy and laser lithotripsy
  • Stone size ≥8 but \< 20 mm in the proximal ureter or kidney. Multiple stones ≤4 are allowed. Bilateral surgeries are allowed
  • Willing to sign informed consent

Exclusion Criteria5

  • Staged surgery
  • Nephrocalcinosis
  • Participant is less than 18 years of age
  • Inability to provide informed consent
  • Members of vulnerable patient populations

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Interventions

PROCEDUREDusting without Moses 2.0 Modulation

Dusting is when a laser is used to break a stone down into tiny fragments that are able to pass through the urine.

PROCEDUREDusting with Moses 2.0 Modulation

Dusting is when a laser is used to break a stone down into tiny fragments that are able to pass through the urine.

OTHERMoses 2.0 Modulation

Lumenis Pulse™ 120H Holmium Laser System with MOSES™ 2.0 Technology used for lithotripsy and BPH treatments


Locations(1)

Northwestern Medicine

Chicago, Illinois, United States

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NCT06346483


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