RecruitingNot ApplicableNCT05718245

HEPA, PM2.5, and Cardiometabolic Health

Using Indoor Air Filtration to Reduce PM2.5 Cardiometabolic Effects in At-risk Individuals


Sponsor

University of Southern California

Enrollment

52 participants

Start Date

Mar 15, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this randomized, double-blind, crossover trial is to test the hypothesis that a longer-term indoor HEPA filtration intervention can improve cardiometabolic profiles by reducing indoor PM2.5 exposures in at-risk individuals.


Eligibility

Min Age: 65 YearsMax Age: 84 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether using HEPA air purifiers in the home can improve cardiometabolic health (heart health, blood sugar regulation, and related markers) in older adults in Los Angeles who are exposed to fine particle air pollution (PM2.5). Fine particulate matter from traffic and other sources has been linked to heart disease, and reducing indoor exposure may have measurable health benefits. You may be eligible if: - You are between 65 and 84 years old - You have not smoked for at least 1 year - You have a history of BMI of 25 or higher - You speak English or Spanish - You live in Los Angeles County You may NOT be eligible if: - You have diabetes (type 1 or type 2) or a degenerative brain disease such as Alzheimer's or dementia - You are currently receiving active cancer treatment - You already have HEPA filters in your home - You plan to move out of your home within 2 years, or will be away for more than one month - You have a high finger-stick blood glucose reading above 200 mg/dL Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEHEPA filter

HEPA filters with the capacity to reduce PM2.5 levels

DEVICESham filter

sham filters without the capacity to reduce PM2.5 levels


Locations(1)

Keck School of Medicine, University of Southern California

Los Angeles, California, United States

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NCT05718245


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