RecruitingNot ApplicableNCT05794087

The Role of Macrophage Activation in Lung Injury Following Ozone Exposure

Activated Macrophages and Ozone Toxicity II


Sponsor

Rutgers, The State University of New Jersey

Enrollment

120 participants

Start Date

Feb 7, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of the study is to better understand the mechanisms of lung injury from ozone exposure. Subjects will participate in two exposure sessions: filtered air and 0.2 ppm ozone. The exposure visits will be at least 2 weeks apart. Subjects will be asked to produce sputum through coughing after each exposure. The samples will be analyzed for macrophage activity.


Eligibility

Min Age: 18 YearsMax Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Clean Air and Ozone for people with air pollution. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 40 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERClean Air

Subjects will be exposed to clean air for 3 hours.

OTHEROzone

Subjects will be exposed to 0.2 ppm ozone for 3 hours.


Locations(1)

Rutgers - EOHSI

Piscataway, New Jersey, United States

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NCT05794087


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