RecruitingNot ApplicableNCT05726058

Ocular Blood Flow Imaging for Glaucoma Assessment

Sponsor

University of Maryland, Baltimore

Enrollment

150 participants

Start Date

Mar 30, 2023

Study Type

INTERVENTIONAL

Conditions

Glaucoma

Summary

The goal of this clinical trial is to investigate the use of an FDA-cleared retinal blood flow imaging instrument called the XyCAM RI and XyCAM FC (Vasoptic Medical, Inc., Columbia, MD) in glaucoma management. The main question it aims to answer are: * Can the investigators use blood flow to discriminate between eyes with early-stage glaucoma and variable-matched controls? * Can the investigators validate that the XyCAM FC simultaneously captures both stereo fundus photography and ocular blood flow monitoring? Participants will be * measured for their blood pressure, heart rate, height, and weight * dilated with tropicamide * imaged using the XyCAM RI, fundus photography, optical coherence tomography, and standard automated perimetry * imaged using the XyCAM RI while inhaling 100% oxygen through a mask

Eligibility

Min Age: 18 YearsMax Age: 88 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating a new eye imaging tool that measures blood flow in the eye to help diagnose and monitor glaucoma — a disease that damages the optic nerve and can lead to vision loss. Researchers want to see if this method gives useful information beyond standard eye pressure tests. **You may be eligible if...** - You are 18 or older with normal vision in both eyes - You are either a healthy volunteer, OR - You have been referred for a glaucoma evaluation, OR - You have been diagnosed with moderate to severe glaucoma in at least one eye **You may NOT be eligible if...** - You have other significant eye conditions that would interfere with imaging - You cannot provide informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEXyCAM with oxygen

After the standard imaging protocols, participants will be asked to inhale 100% oxygen through a mask and will be re-imaged using the XyCAM RI or XyCAM FC.