RecruitingNot ApplicableNCT05730933

An Intervention Study to Improve Therapeutic Compliance in Adult Patients With Eosinophilic Esophagitis.


Sponsor

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Enrollment

72 participants

Start Date

Apr 12, 2023

Study Type

INTERVENTIONAL

Summary

In many chronic conditions adherence to long-term treatment is a challenge, also for patients with eosinophilic esophagitis. Interventions, such as behavioral, educational and reminder interventions might improve treatment adherence. With this trial the investigators want to assess the effects of additional education in combination with more frequent follow up and patient reminders on adherence to treatment in adult patients with eosinophilic esophagitis.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Written informed consent
  • Male or female patient
  • Age >18 years
  • Previous diagnosis of EoE, confirmed by histopathology, with the presence of >15 eosinophilic granulocytes per high power field (hpf) in esophageal biopsies
  • Current maintenance treatment for EoE with a PPI or swallowed topical corticosteroids or about to start with these maintenance medications as decided during regular clinical practice

Exclusion Criteria4

  • Severe and clinically unstable concomitant disease that may interfere with the subject's ability to participate in the study
  • Receive investigational treatment during the study
  • Dilation of esophagus required
  • Insufficient Dutch or English language skills to understand patient information leaflets

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Interventions

BEHAVIORALIntervention

Subjects will receive a behavioral intervention with additional education in combination with more frequent follow up and patient reminders


Locations(1)

Amsterdam UMC, location AMC

Amsterdam, Netherlands

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NCT05730933