eosinophilic esophagitis Clinical Trials

33 recruitingLast updated: May 11, 2026

There are 33 actively recruiting eosinophilic esophagitis clinical trials across 15 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4. Top locations include Philadelphia, Pennsylvania, United States, New York, New York, United States, Chapel Hill, North Carolina, United States. Updated daily from ClinicalTrials.gov.


eosinophilic esophagitis Trials at a Glance

33 actively recruiting trials for eosinophilic esophagitis are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Not Applicable with 8 trials, with the heaviest enrollment activity in Philadelphia, New York, and Chapel Hill. Lead sponsors running eosinophilic esophagitis studies include Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Children's Hospital Medical Center, Cincinnati, and IRCCS San Raffaele.

Browse eosinophilic esophagitis trials by phase

Treatments under study

About eosinophilic esophagitis Clinical Trials

Looking for clinical trials for eosinophilic esophagitis? There are currently 27 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new eosinophilic esophagitis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about eosinophilic esophagitis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 33 trials

Recruiting
Not Applicable

The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States

eosinophilic esophagitisDysphagia
National Institute of Allergy and Infectious Diseases (NIAID)70 enrolled3 locationsNCT07027826
Recruiting
Not Applicable

Pediatric Eosinophilic Esophagitis (pedEoE): Effect of Allergen Heat Denaturation on EoE Remission: a Pilot Trial

eosinophilic esophagitis
Universitaire Ziekenhuizen KU Leuven36 enrolled1 locationNCT06381219
Recruiting
Phase 2

A Study in Adult Participants With EoE to Evaluate Vonoprazan 20 mg Compared to Placebo After 12 Weeks and to Evaluate Vonoprazan 20 mg Up to 24 Weeks

eosinophilic esophagitis
Phathom Pharmaceuticals, Inc.80 enrolled41 locationsNCT06851559
Recruiting
Phase 3

Once Daily Versus Twice Daily Budesonide Orodispersible Tablets for Induction of Remission in EoE

eosinophilic esophagitis
Dr. Falk Pharma GmbH308 enrolled26 locationsNCT06596252
Recruiting

A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

Eosinophilic Esophagitis (EoE)
Regeneron Pharmaceuticals350 enrolled54 locationsNCT06693531
Recruiting
Not Applicable

Trial of Partial Enteral Nutrition With Dairy Free Diet in Eosinophilic Esophagitis

Eosinophilic Esophagitis (EoE)
Kate Farms Inc36 enrolled1 locationNCT07234825
Recruiting
Phase 3

A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

Eosinophilic Esophagitis (EoE)
Regeneron Pharmaceuticals20 enrolled8 locationsNCT07112378
Recruiting

Natural History and Genetics of Food Allergy and Related Conditions

eosinophilic esophagitisAtopic DermatitisFood allergy+1 more
National Institute of Allergy and Infectious Diseases (NIAID)1,800 enrolled1 locationNCT02504853
Recruiting

PRospective Registry of Esophageal Motility

achalasiaeosinophilic esophagitisEsophageal Diseases+2 more
IRCCS San Raffaele10,000 enrolled1 locationNCT07506746
Recruiting
Not Applicable

Patient-Centered Decision Support for Eosinophilic Esophagitis

eosinophilic esophagitis
University of Michigan40 enrolled1 locationNCT06817213
Recruiting
Phase 1Phase 2

A Trial to Evaluate EP-104GI in Adults With Eosinophilic Esophagitis (EoE).

eosinophilic esophagitis
Eupraxia Pharmaceuticals Inc.117 enrolled23 locationsNCT05608681
Recruiting

Eosinophilic Gastrointestinal Disorders Registry

eosinophilic esophagitisEosinophilic GastroenteritisEosinophilic Colitis+1 more
Ann & Robert H Lurie Children's Hospital of Chicago500 enrolled1 locationNCT05199532
Recruiting

A Non-interventional Observational Study to Assess Long-term Efficacy and Safety of Dupilumab for the Treatment of Patients (>= 12 Years) With Eosinophilic Esophagitis Under Real-world-conditions in Germany

eosinophilic esophagitis
Sanofi150 enrolled1 locationNCT06695897
Recruiting

Prevalence and Description of FIRE (Food Induced Immediate Response of the Esophagus) in the Pediatric Population With Eosinophilic Esophagitis

eosinophilic esophagitis
University Hospital, Angers40 enrolled2 locationsNCT06972147
Recruiting
Phase 2

Zemaira Eosinophilic Esophagitis Pilot Study

eosinophilic esophagitis
Children's Hospital Medical Center, Cincinnati15 enrolled2 locationsNCT05485155
Recruiting

Changes in Esophageal Distensibility With Proton Pump Inhibitors in Patients With Esophageal Eosinophilia: A Pilot Study

eosinophilic esophagitis
Indiana University10 enrolled2 locationsNCT03312686
Recruiting

Utility of Mucosal Impedance Device in Chronic Esophageal Disorders:

eosinophilic esophagitisGERD
Medical College of Wisconsin50 enrolled1 locationNCT07227506
Recruiting

OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages

eosinophilic esophagitisEosinophilic GastritisEosinophilic Gastrointestinal Disorders (EGIDs)+2 more
Children's Hospital Medical Center, Cincinnati1,350 enrolled19 locationsNCT02523118
Recruiting

Surface EMG Testing on Swallowing in EoE Patients

Eosinophilic Esophagitis (EoE)
Mayo Clinic30 enrolled1 locationNCT07156357
Recruiting
Not Applicable

EDN and Eosinophilic Esophagitis

eosinophilic esophagitis
Assistance Publique - Hôpitaux de Paris60 enrolled1 locationNCT06387030