RecruitingNCT05743426

Disease Outcomes and Toxicities in Patients With Gastrointestinal and Sarcomatous Malignancies


Sponsor

UNC Lineberger Comprehensive Cancer Center

Enrollment

180 participants

Start Date

Mar 17, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This prospective, single-institution, observational study explores disease outcomes and toxicities in subjects with gastrointestinal malignancies and sarcoma (bone and soft tissue) who are being treated with standard-of-care therapies including radiotherapy. Recent advances in treatment approaches affected disease outcomes and toxicities. Prospective monitoring of disease outcomes and toxicities using standardized assessments will provide information about recent changes in the standard of care and further refine treatment approaches and prospective clinical trial design.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This is an observational study tracking the long-term health outcomes and treatment side effects in people with gastrointestinal cancers (such as stomach, colon, rectal, or pancreatic cancer) or sarcomas (cancers of connective tissue). The study collects real-world data rather than testing a new treatment. **You may be eligible if...** - You are 18 years old or older - You have been diagnosed with a gastrointestinal cancer or sarcoma, confirmed by imaging, biopsy, or cytology - You are willing to provide informed consent and follow-up information **You may NOT be eligible if...** - You are unable or unwilling to provide informed consent - You do not expect to be available for follow-up visits at the required intervals after treatment Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERSurvey

Patient Reported Outcome (PRO) questionnaire

OTHERToxicity Assessments

Toxicity Assessments will be performed using the National Cancer Institute Common Terminology Criteria (NCI-CTCAE).


Locations(1)

University of North Carolina at Chapel Hill, Department of Radiation Oncology

Chapel Hill, North Carolina, United States

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NCT05743426


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