Optic Nerve Sheath Ultrasound in Giant Cell Arteritis
The Sonographic Assessment of the Optic Nerve Sheath in Giant Cell Arteritis
Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
285 participants
Aug 1, 2025
OBSERVATIONAL
Conditions
Summary
The Sonographic Assessment of the Optic Nerve Sheath in Giant Cell Arteritis (SONIC-GCA) study will evaluate the performance of the optic nerve sheath diameter (ONSD), measured via ultrasound, to diagnose and monitor GCA. SONIC-GCA builds upon our previous pilot studies and will answer the following questions: 1. What is the performance of ONSD to identify patients with new-onset, active GCA? 2. Is ONSD useful for monitoring GCA relapses during follow-up? 3. What is the intra- and interobserver reliability of ONSD measurements? 4. Does ONSD differ between patients with and without GCA-related retinal findings?
Eligibility
Plain Language Summary
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Interventions
The patients are examined in a supine relaxed position. The probe is gently placed on the closed eyelid with a standard ultrasound gel and adjusted to a suitable angle to display the optic nerve entry into the eyeball. Measurements are done 3mm distal to the posterior aspect of the ocular globe. Ultrasosonographic 14L5 probe is used with a safe thermal index, mechanical index and intensity limit. All patients will also undergo a bedside fundoscopic examination. Official ophthalmology consultation will be requested in patients with visual symptoms or abnormal fundoscopy.
Clinical assesment, blood test review, temporal/axillary artery ultrasound
Locations(6)
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NCT05749094