RecruitingPhase 2NCT05755113

A Clinical Study to Investigate the Efficacy of Intratumoral Tigilanol Tiglate in Soft Tissue Sarcoma

A Phase IIa Open Label Study Evaluating the Preliminary Efficacy of Intratumoural Tigilanol Tiglate in Advanced and/or Metastatic Soft Tissue Sarcoma of the Extremities and Body Wall.


Sponsor

QBiotics Group Limited

Enrollment

40 participants

Start Date

Apr 13, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

A Phase IIa open label study evaluating the preliminary efficacy of intratumoural tigilanol tiglate in advanced and/or metastatic soft tissue sarcoma of the extremities and body wall.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing tigilanol tiglate, a drug injected directly into tumors, in people with advanced soft tissue sarcoma (a cancer of connective tissue such as muscle, fat, or tendons) located on the body wall or limbs. **You may be eligible if...** - You are 18 or older - You have advanced or metastatic soft tissue sarcoma on the body wall or an arm or leg - Your tumor can be reached with a needle injection (either by feel or with ultrasound guidance) - Your diagnosis has been confirmed by biopsy or pathology **You may NOT be eligible if...** - Your sarcoma is located in a place that cannot be safely injected - Your cancer type is not soft tissue sarcoma - Your overall health does not meet the study's minimum requirements Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGTigilanol Tiglate

Tigilanol tiglate is a novel, short-chain diterpene ester in clinical development for intratumoural treatment of a wide range of solid tumours.


Locations(1)

Memorial Sloan Kettering Cancer Centre

New York, New York, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05755113


Related Trials