SEARCH SAPPHIRE Phase B
SEARCH Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East Africa Phase B
University of California, San Francisco
80,000 participants
Mar 28, 2023
INTERVENTIONAL
Conditions
Summary
This study will evaluate the effects of optimized dynamic prevention and treatment packages delivered in a precision community health model on HIV incidence, as well as other health outcomes, in a community randomized trial design.
Eligibility
Inclusion Criteria3
- Age \>= 15 years
- Living in SEARCH study communities
- Provided informed consent
Exclusion Criteria3
- \<15 years of age
- Living outside SEARCH study communities
- Unable to provide consent or parental co-consent as per country guidelines
Interventions
We will conduct a series of community engagement activities designed to reach persons at risk for HIV, undiagnosed with HIV or diagnosed, or hypertension, and fallen out of care, working closely with community health workers, integrated in the community health system.
Structured approach to provide patient-centered biomedical options for HIV prevention (dynamic choice prevention). Tailored services for HIV treatment support using structured life stage evaluation and assessment plan (LEAP) for youth, pregnant women, and persons with or at risk of HIV viral non-suppression, that includes counselling for heavy alcohol users. Structured approach to offer telehealth for severe hypertension follow up.
Both community-enhanced reach and person-centered delivery will be strengthened through a customized in-country Ministry of Health-compatible community health worker smartphone app and two-way data system linking community health workers and clinical records.
Standard of Care in Uganda and Kenya
Locations(2)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05768763