Acute Myeloid Leukemia At Initial Diagnosis and/or Relapse in Children, Teenagers and Young Adults: Molecular Profiling, Multidrug Testing and MSC Interaction Studies

This research study is collecting biological samples and data from children, teenagers, and young adults (up to age 25) with acute myeloid leukemia (AML) — a fast-growing blood cancer — or from those at genetic risk of developing AML. The goal is to better understand the disease at the molecular level and find new ways to test potential treatments. **You may be eligible if...** - You are between 0 and 25 years old - You have been newly diagnosed with AML, or your AML has relapsed or is not responding to treatment - You carry a genetic predisposition to AML - You are a patient without a blood cancer who needs a bone marrow test as part of standard care (as a comparison group) **You may NOT be eligible if...** - You refuse to participate - You have chronic myeloid leukemia (CML), which is a different blood cancer - You do not have health insurance coverage Talk to your doctor to see if this trial is right for you.