RecruitingNCT05775484
Exercise to Slow Cardiovascular Ageing Progression
Sponsor
National Heart Centre Singapore
Enrollment
450 participants
Start Date
May 1, 2023
Study Type
OBSERVATIONAL
Conditions
Summary
In ageing, deleterious alterations in cardiovascular (CV) structure and function increase risks of ageing-related cardiovascular disease (CVD). Investigators found that these CV alterations were associated with circulating serum metabolites, suggesting a metabolic basis to CV ageing. Investigators hypothesize that modification of these metabolites by intervention, such as exercise, may retard CV alterations and reduce CVD in ageing.
Eligibility
Min Age: 21 YearsMax Age: 100 Years
Inclusion Criteria2
- Age >=21 years old
- Outdoor ambulant
Exclusion Criteria11
- Wheelchair or bed-bound
- Dementia
- Residing in sheltered or nursing home
- Cancer
- Participation in ongoing clinical trials that involve interventional drugs or devices
- Aneurysms
- Acute infections (in the last six months)
- Uncontrolled thyrotoxicosis
- Neuromuscular, musculoskeletal or rheumatoid disorders that are exacerbated by exercise
- Uncontrolled asthma or chronic lung disease
- Restrictive lung disease
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05775484
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