Cardiovascular Clinical Trials

27 recruiting

Cardiovascular Trials at a Glance

670 actively recruiting trials for cardiovascular are listed on ClinicalTrialsFinder across 6 cities in 80 countries. The largest study group is Not Applicable with 259 trials, with the heaviest enrollment activity in Boston, New York, and Seoul. Lead sponsors running cardiovascular studies include National Heart, Lung, and Blood Institute (NHLBI), Chinese University of Hong Kong, and The Cleveland Clinic.

Browse cardiovascular trials by phase

Treatments under study

About Cardiovascular Clinical Trials

Looking for clinical trials for Cardiovascular? There are currently 27 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cardiovascular trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cardiovascular clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 670 trials

Recruiting

Heart Health Study in Washington D.C. to Develop a Community-Based Behavioral Weight Loss Intervention

ObesityCardiovascular Disease
National Heart, Lung, and Blood Institute (NHLBI)200 enrolled1 locationNCT01927783
Recruiting
Phase 2Phase 3

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis

Atherosclerotic Cardiovascular Disease
CSL Behring2,310 enrolled542 locationsNCT05485961
Recruiting

Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

Cardiovascular (CV) Risk
National Heart, Lung, and Blood Institute (NHLBI)250 enrolled1 locationNCT04014348
Recruiting

Diabetes and Heart Disease Risk in Blacks

ObesityCardiovascular DiseasesHypertension+1 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,000 enrolled1 locationNCT00001853
Recruiting
Phase 3

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

Cardiovascular Disease
Amgen11,000 enrolled243 locationsNCT07136012
Recruiting

Awareness of Risk Factors and Perception of Cardiovascular Risk in Secondary Prevention Among Women and Men

Cardiovascular Disease
Istituti Clinici Scientifici Maugeri SpA200 enrolled1 locationNCT07521436
Recruiting

Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging

Normal and Abnormal Cardiovascular Physiology
National Heart, Lung, and Blood Institute (NHLBI)5,000 enrolled1 locationNCT03581318
Recruiting
Phase 3

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Cardiovascular DiseasesHypertensionDiabetes Mellitus, Type 2
Boehringer Ingelheim11,800 enrolled1152 locationsNCT07064473
Recruiting

Hypertension Explored in Long-term Postpartum Follow-up in Later Life

Cardiovascular DiseasesHypertensionCerebrovascular Disorders+1 more
University of Oxford200 enrolled1 locationNCT06187012
Recruiting
Not Applicable

SMART to Optimize an Intervention to Maintain Health Improvements After Cardiac Rehabilitation

Cardiovascular DiseasesCardiac Rehabilitation
The Miriam Hospital400 enrolled1 locationNCT06886789
Recruiting
Not Applicable

Randomized, Double-blind Crossover Trial Comparing Low-GI Functional vs. Standard Wholegrain Carbohydrates on Glycolipid Metabolism and Vascular Stress Markers in Adults With Suboptimal Triglyceridemia

InflammationNutritionDiabetes Prevention+1 more
University of Bologna40 enrolled1 locationNCT07198789
Recruiting
Phase 2Phase 3

Focusing on the Menopausal Transition to Improve Mid-Life Women's Health

MenopauseMenopause Related ConditionsCardiovascular+1 more
University of Colorado, Denver200 enrolled1 locationNCT06975111
Recruiting
Phase 2

Efficacy, Safety, and PopPK Profile of ABP-745 in Patients With Atherosclerosis

ASCVDAtherosclerosis Cardiovascular DiseaseASCVD Management
Atom Therapeutics Co., Ltd200 enrolled33 locationsNCT07303777
Recruiting

Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank

Williams SyndromeCardiovascular DiseaseSupravalvular Aortic Stenosis
National Heart, Lung, and Blood Institute (NHLBI)1,099 enrolled3 locationsNCT02706639
Recruiting

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

HypertensionCardiovascular DiseaseAdrenal Gland Neoplasm+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,150 enrolled1 locationNCT03374215
Recruiting

Cardiovascular Health Improvement Project

Heart FailureCardiovascular DiseasesAortic Aneurysm+2 more
University of Michigan15,000 enrolled1 locationNCT02306200
Recruiting

Prevalence, Incidence and Risk Signature of Chronic Kidney Disease in Sub-Saharan Africa

ObesityCardiovascular DiseasesChronic Kidney Diseases+8 more
Swiss Tropical & Public Health Institute1,200 enrolled1 locationNCT05881447
Recruiting

Identifying Risk Factors and Predicting Future Health Outcomes for Korean Patients With Heart and Blood Vessel Diseases: A Long-term Follow-up Study

Cardiovascular Diseases (CVD)Cerebro Vascular Disease
Samsung Medical Center800,000 enrolled1 locationNCT07393412
Recruiting

Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)

Cardiovascular DiseaseUndiagnosed Diseases
National Heart, Lung, and Blood Institute (NHLBI)10,000 enrolled1 locationNCT02543996
Recruiting
Phase 3

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

ObesityOverweightAtherosclerotic Cardiovascular Disease
Amgen12,800 enrolled759 locationsNCT07037433