Menthol for Dyspnea Relief in Health and COPD
Effectiveness and Mechanisms of Menthol Inhalation for the Relief of Dyspnea in Health and COPD
KU Leuven
120 participants
Jan 1, 2023
INTERVENTIONAL
Conditions
Summary
Menthol inhalation (MI) is a novel and promising treatment option for acute relief of dyspnea, however, the underlying ventilatory and/or neural related mechanisms for this relief in symptoms remain unknown. The overall aim of this research project is to systematically examine the mechanisms of dyspnea relief from MI in healthy individuals and those with COPD.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
300 milligrams of L-menthol will be deposited on to a cellulose swab and secured inside the lower portion of a sealed facemask.
600 microliters of 100% natural strawberry flavoring will be deposited onto on to a cellulose swab and secured inside the lower portion of a sealed facemask.
Menthol will be administered using a noseplug and facial airflow will be applied with a tabletop fan.
Strawberry will be administered using a noseplug and airflow to the leg will be applied with a tabletop fan.
Menthol will be administered using a noseplug and airflow to the leg will be applied with a tabletop fan.
Strawberry will be administered using a noseplug and facial airflow will be applied with a tabletop fan.
Locations(1)
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NCT05785026