RecruitingNCT05785793

Autoimmune Hepatitis Cohort in China

Clinical Characteristics and Outcomes of Autoimmune Hepatitis: a Retro-prospective Multicenter Cohort in China

Sponsor

Shanghai Jiao Tong University School of Medicine

Enrollment

1,000 participants

Start Date

Feb 1, 2023

Study Type

OBSERVATIONAL

Conditions

Autoimmune Hepatitis

Summary

The goal of this observational study is to describe the clinical features and long-term prognosis in patients diagnosed with autoimmune hepatitis (AIH) in China and assess the effectiveness and safety of AIH treatment options in a real-world setting.

Eligibility

Min Age: 14 Years

Inclusion Criteria4

Age ≥ 14 years
Probable or definite diagnosis of autoimmune hepatitis according to the International Autoimmune Hepatitis Study Group criteria
Availability of all following essential parameters at the initial diagnosis of AIH: including alanine transaminase, aspartate aminotransferase, total bilirubin, alkaline phosphatase, immunoglobulin G, and platelet count
Provide informed consent

Exclusion Criteria4

Have a concomitant diagnosis of primary biliary sclerosis, primary sclerosing cholangitis, immunoglobulin G 4-related cholangitis
Have an active infection with hepatitis B virus, hepatitis C virus, hepatitis delta virus, HIV, cytomegalovirus, or Epstein-Barr virus
Have a concomitant diagnosis of hepatocellular carcinoma or other malignant diseases before the diagnosis of AIH
Considered ineligible to the enrollment in the clinical study by the researcher

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