RecruitingNot ApplicableNCT05787834

Home-based Respiratory Muscle Training for Minimizing Side Effects in Patients Undergoing Treatment for Breast Cancer

Respiratory Muscle Training During Breast Cancer Treatment: Effects on the Autonomic Nervous System and Cardiotoxicity

Sponsor

Roswell Park Cancer Institute

Enrollment

130 participants

Start Date

Oct 16, 2023

Study Type

INTERVENTIONAL

Conditions

Breast Carcinoma

Summary

This clinical trial evaluates whether home-based respiratory muscle training is useful for minimizing side effects in patients undergoing treatment for breast cancer. Over-activation of the nervous system during breast cancer treatment can result in heart- and lung-related side effects which have the potential to reduce a patient's quality of life. Aerobic exercise can help prevent the development of these side effects. However, engaging in regular aerobic exercise may be difficult for breast cancer patients who are actively undergoing treatment. Respiratory muscle training (RMT) involves a series of breathing and other exercises that are performed to improve the function of the respiratory muscles through resistance and endurance training. Home-based RMT may represent a more feasible approach for reducing side effects in patients undergoing treatment for breast cancer.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether home-based breathing muscle exercises can help reduce the side effects of chemotherapy in people being treated for breast cancer. Chemotherapy can weaken respiratory muscles, and researchers want to see if targeted breathing training during treatment can protect lung health and improve recovery. **You may be eligible if...** - You have been diagnosed with breast cancer and are scheduled to receive chemotherapy (before or after surgery) - You are 18 or older - You are cognitively able to follow directions and perform the breathing exercises - You can speak, read, and understand English **You may NOT be eligible if...** - You have uncontrolled infections, heart failure, unstable chest pain, or serious heart rhythm problems - You have had prior radiation to the left chest wall - You are pregnant or nursing - Your doctor considers you medically too frail to participate Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.