RecruitingNCT05790785

Vascular Complications in Children From T1D Diagnosis

Understanding Vascular Complications in Children From Type 1 Diabetes Diagnosis


Sponsor

University of British Columbia

Enrollment

150 participants

Start Date

Mar 25, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Cardiovascular disease is a complication of type 1 diabetes (T1D), a life-long disease, usually diagnosed in childhood. The goal of this project is to determine the timing and factors leading to vascular damage in children from T1D diagnosis.


Eligibility

Min Age: 8 YearsMax Age: 18 Years

Inclusion Criteria3

  • Between the ages of 8-18 years
  • Within 14 weeks of type 1 diabetes diagnosis
  • Ability and willingness to undergo non-invasive arterial stiffness assessment for 1hr and willingness to wear the 24-h automated blood pressure monitoring (ABPM) device.

Exclusion Criteria6

  • Children will be ineligible to participate in the study if they meet any of the following:
  • Other cardiometabolic or endocrine diseases diagnosis (type 2 diabetes; familial disorders of cholesterol metabolism; lupus)
  • Other genetic syndromes (Down Syndrome; Prader-Willi)
  • Eating disorder diagnosis
  • Transgender children taking hormone blockers or exogenous sex steroids
  • Currently treated with medications known to affect metabolism (e.g. glucocorticoids, antipsychotics).

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Locations(1)

Endocrine and Diabetes Unit, BC Children's Hospital

Vancouver, British Columbia, Canada

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NCT05790785


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