Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors

This study is testing the safety of a new drug called RAD301, first in healthy volunteers and then in patients with specific solid tumors — including pancreatic cancer, lung cancer, esophageal cancer, cervical cancer, endometrial cancer, and ovarian cancer. **You may be eligible if...** - You are 18 or older and able to give informed consent - For cancer patients: you have a confirmed diagnosis of one of these cancers (pancreatic, non-small cell lung, esophageal squamous, cervical, endometrial, or ovarian cancer) with at least one site of active or residual disease on recent imaging - For healthy volunteers: you must meet separate health screening criteria **You may NOT be eligible if...** - You have a cancer type not listed in the study - Your most recent scan is more than 12 weeks old and has not been confirmed by the study sponsor - Other health conditions or prior treatments disqualify you Talk to your doctor to see if this trial is right for you.