Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

This study is evaluating whether adjusted (lower-dose) chemotherapy regimens can be safely and effectively used for lung cancer patients who are older, frail, or have other health conditions that make standard full-dose chemotherapy too risky. **You may be eligible if:** - You are over 18 years old with Stage IV lung cancer (small cell or non-small cell), or Stage III if standard treatments are not appropriate for you - You are considered a "compromised" patient — this may include older age, frailty, poor organ function, or other health conditions - Your doctor plans to treat you with a chemotherapy regimen that includes at least one standard chemotherapy drug - You have measurable cancer on imaging **You may NOT be eligible if:** - You are under 18 - You are not planned to receive chemotherapy - Your brain metastases are causing active symptoms requiring ongoing steroid treatment - You cannot consent to the study - You are pregnant Talk to your doctor to see if this trial is right for you.