RecruitingNCT05817617

Vitamin D and Head and Neck Cancer: Impact on Toxicity and Prognosis

Vitamin D and Head and Neck Cancer: Impact on Toxicity and Prognosis: Prospective Multicenter Study of Head-Neck Group of the Italian Association of Radiotherapy and Clinical Oncology (AIRO)


Sponsor

Centro di Riferimento Oncologico - Aviano

Enrollment

953 participants

Start Date

Aug 8, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to learn about relation between vitamin D levels in subjects with head and neck cancer. The main question it aims to answer are: * variation of vitamin D levels in the study population at different time points * relation between therapy side effects and vitamin D level * relation between disease outcome and vitamin D level Participants will be followed as per clinical practice


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study looks at whether vitamin D levels affect how well people with head and neck cancer tolerate radiation therapy and how their cancer responds. Researchers will measure vitamin D levels in patients before, during, and after radiation to find out if having enough vitamin D can help reduce side effects and improve treatment outcomes. **You may be eligible if...** - You have been diagnosed with head and neck cancer (squamous cell type) - Your cancer is locally advanced (has not spread to distant organs) - You are scheduled to receive radiation therapy (with or without chemotherapy) - You will receive radiation to both sides of the neck **You may NOT be eligible if...** - Your cancer has spread to distant parts of the body - You have a known disorder affecting how your body processes calcium or vitamin D Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(10)

Ospedale Mons AR Dimiccoli

Barletta, BAT, Italy

Centro di Riferimento Oncologico - Aviano

Aviano, Pordenone, Italy

Ospedale dell'Angelo

Mestre, Venezia, Italy

Ospedali Riuniti

Ancona, Italy

AORN San Pio

Benevento, Italy

IEO

Milan, Italy

Ospedale Niguarda

Milan, Italy

Ospedale del Mare

Naples, Italy

Azienda Ospedaliero Universitaria di Pisa

Pisa, Italy

Policlinico Umberto I

Roma, Italy

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NCT05817617


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