RecruitingNot ApplicableNCT05820646

Effect of Boswellia Sacra as an Intracanal Medicament on Postoperative Pain Intensity and Bacterial Load Reduction

Effect of Boswellia Sacra Versus Calcium Hydroxide as an Intracanal Medicament on Postoperative Pain Intensity and Bacterial Load Reduction in Necrotic Mandibular Premolars: A Randomized Clinical Trial


Sponsor

Cairo University

Enrollment

45 participants

Start Date

May 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This research will study the effect of Boswellia Sacra versus calcium hydroxide as an intracanal medicament on postoperative pain intensity measured using numerical rating scale (NRS) and bacterial load reduction reduction determined by bacterial counting using agar culture technique after root canal preparation (CFU/ml) in mandibular premolars with necrotic pulp.


Eligibility

Min Age: 25 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This dental study tests whether Boswellia sacra — an herbal extract derived from frankincense resin — can reduce pain after root canal treatment when used as a temporary dressing inside the tooth canal. Researchers want to compare it to a standard dressing to see if this natural extract helps manage post-treatment pain. **You may be eligible if...** - You are between 25 and 45 years old - You have a single lower premolar tooth with one root canal that has been diagnosed with a dead (necrotic) pulp - You have pain when the tooth is tapped or pressed but no swelling - You are otherwise healthy (ASA class I or II) **You may NOT be eligible if...** - You have a severe gum pocket around the tooth - You are pregnant or have significant health conditions - You have had antibiotics, anti-inflammatory drugs, or root canal treatment on that tooth recently - You have active swelling, a cyst, or a sinus tract near the tooth Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERBoswellia Sacra

1. Boswellia Sacra used as an intracanal medicament for 3 days 2. Boswellia Sacra used as an intracanal medicament for 7 days


Locations(1)

Cairo University Hospital ,Endodontic clinic

Giza, Manial, Egypt

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NCT05820646


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