RecruitingNCT05826067

Study of E. Coli Isolates From Recurrent Urinary Tract Infections

Systematic Analysis of Bacterial Multidrug Tolerance in Longitudinal Isolates of Patients That Are Prone to Developing Urinary Tract Infections

Sponsor

Université Catholique de Louvain

Enrollment

45 participants

Start Date

Apr 20, 2023

Study Type

OBSERVATIONAL

Conditions

Urinary Tract Infections Patients With Suprabubic Catheter Patients With Nephrostomy Catheter

Summary

Prospective study aiming at collecting clinical Escherichia coli isolates from patients with recurrent urinary tract infection; samples to be collected during routine procedures.

Eligibility

Min Age: 18 Years

Inclusion Criteria3

patients hospitalized for urinary tract infection, with or without neurological disorders (spina bifida, MS, paraplegic patients) or ambulatory patients diagnosed with a urinary tract infection when the identified causative agent is E. coli
patients who have or are planned to undergo the insertion of a suprapubic catheter
patients who have or are planned to undergo the insertion a nephrostomy catheter

Exclusion Criteria4

refusing the planned treatment
with therapy compliance
pregnant women
who do not consent to participate

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Interventions

OTHERcollection of bacterial strains

Urine (and blood) samples will be collected following SOC procedures for diagnostic purposes, at each visit of the patient (initial visit, follow up study or visit for new episode. For patients needing a catheter, urine sample will be collected before the insertion of the catheter, and before renewal of the catheter. Catheter tips will also be collected and sonicated to isolate bacteria. E. coli will be stored for analysis.