Immediate Versus Delayed Loading of Single Posterior Zirconia Implants
Immediate Versus Delayed Loading of Single Posterior Zirconia Implants: A Multicenter Randomized Controlled Clinical Trial
University of Milan
220 participants
Dec 1, 2022
INTERVENTIONAL
Conditions
Summary
The main aim of the present study is to investigate implant success rate after 5 years of function of immediate (Test group; within 7 days of implant placement) versus delayed (Control group; 8 weeks after implant placement) loading of two-pieces zirconia implant, placed in pristine bone without bone regeneration. Implant success rate will be defined according to Buser's criteria. Secondary endpoints: Marginal bone level (MBL) evaluation by means of standardized radiographs; Clinical evaluation of biological (e.g. Plaque Index, PI; Probing Pocket Depth, PPD, Bleeding on Probing, BOP; suppuration upon probing/palpation) and prosthetic/technical complications; Clinical evaluation of soft tissue width, keratinized tissue, marginal and interproximal soft tissue recession; Patient reported outcome measures (PROMs) by questionnaire administration:
Eligibility
Inclusion Criteria8
- Sistemically healthy patients
- partial edentulism
- premolar position
- molar position
- Bone width and height at least 6 and 10mm, respectively.
- Keratinized tissue, at least 1 mm at implant site
- Full understanding of the proposed surgical treatments and the protocol schedule
- Full comprehension and availability to sign the informed consent form
Exclusion Criteria12
- Heavy smokers (\>10 cigarettes a day)
- Serious kidney or liver diseases
- Uncontrolled diabetes
- Bisphosphonates intake
- History of radiotherapy of the head and neck
- Current antiblastic chemotherapy
- Congenital (primary) or acquired (secondary) immunodeficiency
- Pregnant women
- Connective tissue disorders
- untreated stage III/IV periodontitis
- Autoimmune diseases
- oral parafunctions
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Interventions
(Test group; within 7 days of implant placement) versus delayed (Control group; 8 weeks after implant placement)
Locations(1)
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NCT05838365