RecruitingNCT05840575

Investigating Cognitive Impairment in Young Patients With Cancer Prospectively

A Multidisciplinary Neuroscience Approach to Investigate Cognitive Impairment in Young Patients With Cancer Prospectively


Sponsor

Rigshospitalet, Denmark

Enrollment

100 participants

Start Date

Mar 1, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The MyBrain study investigates the brain function of children, adolescents and young adults during and after chemo treatment for cancer. The tests include 1) cognitive skills such as memory and attention; 2) the brain's electrical activity; 3) and biological markers related to brain function. The aim of the study is to better understand the trajectories of cognitive functioning and measures that have been associated with cognitive impairment in patients treated with chemotherapy.


Eligibility

Min Age: 7 YearsMax Age: 29 Years

Inclusion Criteria3

  • Patients who are newly diagnosed with a non-CNS cancer and will undergo chemotherapy at University Hospital Copenhagen, Rigshospitalet.
  • At the age of 7-29 years at diagnosis
  • Each patient is matched (1:1) with a control participant within 24 months of age. The controls are recruited from the patient's own social circle and can be a friend, partner, or close family (sibling or cousin).

Exclusion Criteria5

  • Unable to speak and understand Danish
  • Severe intellectual disability or mental health disorder that hinders participation
  • Brain metastases,
  • Terminal illness
  • Have had a previous chemotherapy or radiotherapy treatment

Locations(1)

Rigshospitalet

Copenhagen, Denmark

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NCT05840575


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