Childhood Cancer Clinical Trials

49 recruitingLast updated: June 18, 2026

There are 49 actively recruiting childhood cancer clinical trials across 23 countries. Studies span Not Applicable, Phase 2, Phase 1. Top locations include Memphis, Tennessee, United States, Geneva, Switzerland, Bern, Switzerland. Updated daily from ClinicalTrials.gov.


Childhood Cancer Trials at a Glance

49 actively recruiting trials for childhood cancer are listed on ClinicalTrialsFinder across 6 cities in 23 countries. The largest study group is Not Applicable with 25 trials, with the heaviest enrollment activity in Memphis, Geneva, and Bern. Lead sponsors running childhood cancer studies include St. Jude Children's Research Hospital, University of Bern, and Dana-Farber Cancer Institute.

Browse childhood cancer trials by phase

Treatments under study

About Childhood Cancer Clinical Trials

Looking for clinical trials for Childhood Cancer? There are currently 35 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Childhood Cancer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Childhood Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 49 trials

Recruiting

Protocol For Collecting Data On Patients With Childhood Cancer

Childhood Cancer
St. Jude Children's Research Hospital30,000 enrolled1 locationNCT00684580
Recruiting
Not Applicable

Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer: A Randomized Clinical Trial

Chronic PainChildhood Cancer Survivor
St. Jude Children's Research Hospital228 enrolled1 locationNCT07160621
Recruiting
Not Applicable

Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia

InsomniaAcute Lymphoblastic Leukemia ALLSurvivor of Childhood Cancer
St. Jude Children's Research Hospital40 enrolled1 locationNCT07191119
Recruiting
Not Applicable

Patients At Risk for Sensory Screening (HPARSS) to Enhance Sensory Deficit Screening in Childhood Cancer Survivors

Childhood Cancer
Washington University School of Medicine146 enrolled1 locationNCT05582551
Recruiting
Not Applicable

Light Therapy for Chemotherapy Induced Peripheral Neuropathy in Childhood Cancer Survivors

Chemotherapy Induced Peripheral NeuropathyCancerChildhood Cancer
Yale University20 enrolled2 locationsNCT07019259
Recruiting
Not Applicable

Feasibility of Incorporating a Standardized Substance Use Measure With Linked-Brief Intervention Into Routine Psychosocial Care of Adult Childhood Cancer Survivors

Substance UseSurvivors of Childhood Cancer
St. Jude Children's Research Hospital30 enrolled1 locationNCT07516301
Recruiting
Phase 1Phase 2

CANnabinoids in Pediatric ONCology

CancerChildhood Cancer
University of Manitoba60 enrolled3 locationsNCT05754840
Recruiting

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

InfertilityAcute Ovarian FailureEarly Menopause And Infertility In Females After Treatment For Childhood Cancer
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)100 enrolled1 locationNCT05440617
Recruiting

Cardiac Dysfunction in Childhood Cancer Survivors

Cardiac dysfunctionCardiovascular DiseasesChildhood Cancer
University of Bern500 enrolled6 locationsNCT03790943
Recruiting
Not Applicable

A Study of Time-Restricted Eating in Childhood Cancer Survivors

Childhood Cancer Survivors
Memorial Sloan Kettering Cancer Center300 enrolled4 locationsNCT07009288
Recruiting
Not Applicable

Male Fertility Preservation Using Cryopreservation of Testicular Tissue Before Highly Gonadotoxic Cancer Treatment

Childhood CancerFertility Disorders
Gumy-Pause Fabienne100 enrolled3 locationsNCT03180918
Recruiting
Not Applicable

Heuristic Tool To Improve Symptom Self-Management in Adolescents and Young Adults With Cancer

CancerChildhood CancerSymptoms and Signs
Virginia Commonwealth University126 enrolled5 locationsNCT05958316
Recruiting
Not Applicable

Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors

Muscle WeaknessChildhood Cancer
St. Jude Children's Research Hospital60 enrolled1 locationNCT06819475
Recruiting

Assessing and Addressing Health-Related Social Needs Among Families of Children With Cancer

Caregiver social supportChildhood CancersCaregiver Distress+1 more
Wake Forest University Health Sciences60 enrolled1 locationNCT07278414
Recruiting
Not Applicable

Assessment of Remote Approaches for Identification of Autonomic Dysfunction Among Survivors of Leukemia and Lymphoma

Childhood Cancer
St. Jude Children's Research Hospital188 enrolled1 locationNCT06747910
Recruiting
Not Applicable

Proof-of-Concept Testing of the Cardiovascular Health Equity Through Food (CHEF) Intervention in Childhood Cancer Survivors

Childhood Cancer SurvivorsChildhood Cancer
Dana-Farber Cancer Institute17 enrolled2 locationsNCT06609473
Recruiting
Not Applicable

Cohort Evaluation of Body Fluids Early Detection of Cancer in High-risk Individuals

Risk of Breast CancerRisk of Gynaecological CancerRisk of Colorectal Cancer+14 more
Gustave Roussy, Cancer Campus, Grand Paris5,909 enrolled1 locationNCT06907095
Recruiting

Validation of a Rapid Screening Tool for Anxiety-depressive Disorders in Children, Adolescents and Young Adults Treated in Oncology. Multicenter Study.

Depression, AnxietySurvivors of Childhood CancerGeneralized Anxiety+1 more
Centre Hospitalier Universitaire de Saint Etienne545 enrolled7 locationsNCT07117058
Recruiting
Not Applicable

SchoolCare: A Social Intervention Introducing Telepresence Robots and School Navigation to Reduce School Fragmentation for Children Undergoing Cancer Treatment

Childhood Cancer SurvivorsSchool AttendanceAcademic Level+1 more
Rigshospitalet, Denmark128 enrolled3 locationsNCT07398677
Recruiting

Biomarkers of Brain Injury in Children With Brain Tumors

Brain TumorChildhood CancerChildhood Brain Tumor
Uppsala University560 enrolled1 locationNCT07381959