RecruitingNot ApplicableNCT05843695

Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety

Enhancing Intensive Transdiagnostic Cognitive Behavioral Therapy for Veterans With PTSD and Anxiety Disorders


Sponsor

Baylor College of Medicine

Enrollment

306 participants

Start Date

Sep 22, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to compare two different intensive formats of delivering cognitive-behavioral treatment for people with PTSD and anxiety disorders. The main questions it aims to answer are: * Is iTCBT delivered in individual and group formats more effective than TAU in improving anxiety symptoms and quality of life? * For treatment non-responders, is iTCBT-Enhanced more effective than TAU improving anxiety symptoms and quality of life? * Does iTCBT-Individual produce a larger improvement in anxiety and quality of life compared with iTCBT-Group? Participants will undergo several assessments throughout the course of the study. Based on randomization, they will receive: (1) iTCBT in an individual format over a 2-week period, (2) iTCBT in a group format over a 2-day period, or (3) usual care. Those who do not show a response to treatment will receive 4 additional individual therapy sessions.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether adding a specific skill-building component to standard psychotherapy improves outcomes for veterans and active service members with PTSD or anxiety disorders. The goal is to enhance existing therapy by boosting positive emotions and life satisfaction — not just reducing symptoms. **You may be eligible if...** - You are a veteran or active service member aged 18 or older - You have a current diagnosis of at least one anxiety-based disorder (PTSD, panic disorder, social anxiety, generalized anxiety, or related conditions) - You report moderate-to-poor life satisfaction - You have been on a stable psychiatric medication dose for at least 4 weeks **You may NOT be eligible if...** - You do not have a qualifying anxiety or trauma-related diagnosis - You are currently in active mental health crisis (such as active suicidal ideation) - You are not willing to be randomly assigned to a treatment condition Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALiTCBT-I

Individual format over 2 weeks

BEHAVIORALiTCBT-G

Group format over 2 days

BEHAVIORALTAU

Standard care


Locations(1)

Michael E. DeBakey VA Medical Center

Houston, Texas, United States

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NCT05843695


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