RecruitingNot ApplicableNCT05845905

Effects of Remote Ischemic Conditioning on Blood Pressure in Older Patients With Hypertension


Sponsor

Yi Yang

Enrollment

158 participants

Start Date

May 10, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to learn about effects of remote ischemic conditioning on blood pressure in older patients with essential hypertension.


Eligibility

Min Age: 65 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a technique called Remote Ischemic Conditioning (RIC) — which involves briefly and repeatedly reducing blood flow to the arm using a blood pressure cuff — can help lower high blood pressure in older adults. **You may be eligible if...** - You are between 65 and 85 years old - You have high blood pressure (hypertension) with a systolic reading of 140 mmHg or higher - You are willing to participate and sign the consent form **You may NOT be eligible if...** - You have had a stroke, heart attack, or significant cardiovascular event in the past 3 months - You have severe heart failure or other serious heart conditions - You have arm conditions (like lymphedema or blood clots) that prevent using a blood pressure cuff - You have severe kidney disease or other major organ failure - You are already participating in another clinical trial Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURERemote ischemic conditioning

Remote ischemic conditioning (RIC) is induced by 4 cycles of 5 min of upper limb ischemia followed by 5 min reperfusion. Limb ischemia was induced by the inflation of an automated cuff to the pressure rising by 20 mmHg from baseline systolic pressure. RIC will be conducted twice daily for 7 days.

PROCEDURESham remote ischemic conditioning

Sham-RIC is performed in the same way as the treatment group except that the blood pressure cuff is inflated to 60 mmHg, which produces mild pressure sensations but has no blocking impact on blood flow.


Locations(1)

First Hospital of Jilin University

Changchun, Jilin, China

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NCT05845905


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