RecruitingNCT05847634

Depth of Sedation and Its Impact on Cerebrovascular Reactivity in Acute Respiratory Distress Syndrome: a Pilot Analysis

Sponsor

University of Manitoba

Enrollment

40 participants

Start Date

Nov 25, 2024

Study Type

OBSERVATIONAL

Conditions

ARDS, Human

Summary

Investigation of the feasibility of monitoring processed transcutaneous electroencephalography (EEG), a method of interpreting brain activity, and near-infrared spectroscopy (NIRS), a method of determining levels of tissue oxygenation (StO2) in the brain, for patients with acute respiratory distress syndrome (ARDS) in the ICU.

Eligibility

Min Age: 18 Years

Inclusion Criteria5

Adult patient admitted to the ICU
ARDS confirmed according to the Berlin Definition
Invasive mechanical ventilation
Deep sedation and/or neuromuscular blockade required for ARDS treatment at the discretion of the treating medical team
Application of monitoring devices feasible

Exclusion Criteria5

More than 24 hours elapsed since ICU admission
Death is deemed imminent and inevitable during the next 24 hours
Known allergy to a textile component of the device
Consent declined from patient or authorized third party
The treating clinician believes that participation in the study would not be in the best interest of the patient

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Interventions

DEVICEMasimo O3 NIRS cerebral oximetry and SedLine processed EEG

Non-invasive neuromonitoring device for observational study

Locations(1)

Health Sciences Centre Winnipeg

Winnipeg, Manitoba, Canada

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NCT05847634

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