Trans-cranial Direct Current Stimulation on Alcohol Craving
Exploring the Effect of Trans-cranial Direct Current Stimulation on Craving and Serum BDNF of Patients With Alcohol Dependence
Taipei City Hospital
60 participants
Apr 17, 2023
INTERVENTIONAL
Conditions
Summary
The goal of thisclinical trial is to investigate the efficacy of trans cranial direct current stimulation (tDCS) for alcohol craving in individuals with alcohol dependence. The main question it aims to answer is whether 10 sessions of tDCS can reduce craving for alcohol. Participants will be randomized into active group and sham group. Researchers will compare the severity of craving in these groups.
Eligibility
Inclusion Criteria3
- Be between 20-65 years of age
- have sufficient cognitive function to understand the study and complete the informed consent process
- Be diagnosed with alcohol dependence as defined by DSM-IV through a structured interview (Mini-International Neuropsychiatric Interview, M.I.N.I.)
Exclusion Criteria10
- Intellectual disabilities
- bipolar disorder
- Psychosis (schizophrenia)
- Major physical illness (brain hemorrhage, brain tumor, myocardial infarction, epilepsy or history of seizures)
- intracorporeal electronic or metal implants (e.g., cardiac pacemaker)
- Pregnant or breastfeeding women
- Allergy to headgear and electrode materials
- Trauma or infection to the head
- Intracranial space occupied lesion (such as brain tumor, AVM, etc.) or patients who have undergone brain surgery, meningitis and encephalitis
- Patients who are expected to undergo brain and major surgery during the trial period
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Interventions
The intervention consisted of 20 daily 20-min sessions of bilateral prefrontal tDCS
The sham group consisted of 10 daily 20-min sessions of sham stimulation
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05854693