Postoperative Hypofractionated Radiation in Cervical and Endometrial Tumours: Phase II Study

This study is testing whether a shorter, higher-dose radiation schedule (hypofractionation — fewer sessions with larger doses per session) after hysterectomy is as safe and effective as the standard longer radiation schedule for women with cervical or endometrial (uterine) cancer. **You may be eligible if...** - You have been diagnosed with cervical or endometrial cancer and have had a hysterectomy - Your doctors have recommended radiation therapy to the pelvis after surgery - Your cancer had intermediate or high-risk features that make radiation necessary - You are in generally good health (ECOG 0–2) **You may NOT be eligible if...** - You have visible remaining cancer after surgery - You need radiation that extends to the lymph nodes near the aorta (para-aortic region) - You have HIV - You have had pelvic radiation before - You have a prior cancer treated with chemotherapy - You have pre-existing bowel or bladder conditions that would make it hard to assess side effects Talk to your doctor to see if this trial is right for you.