RecruitingNot ApplicableNCT05859048

Multidisciplinary Approach for High Risk Patients Leading to Early Diagnosis of Canadians in Heart Failure

Multidisciplinary Approach for High Risk Patients Leading to Early Diagnosis of Canadians

Sponsor

Cardiology Research UBC

Enrollment

1,360 participants

Start Date

Mar 1, 2024

Study Type

INTERVENTIONAL

Conditions

Heart Failure

Summary

The goal of this study is improve the screening of heart failure and identify patients early who are at risk of heart failure. The main question\[s\] it aims to answer are: • will an electronic health records (EHR) case finding algorithm for heart failure, followed by N-Terminal pro-brain natriuretic peptide (NT-proBNP) screening and artificial intelligence (AI) echocardiogram compared to usual care identify patients at risk for heart failure earlier than standard of care? Participants will be enrolled and randomized to either standard of care (SOC) or intervention arm: SOC arm: electronic health records will be reviewed over six months for assessments performed to identify heart failure. Intervention arm: blood sample for N-terminal prohormone of B-type natriuretic peptide (NT-proBNP) at local laboratory . For elevated NT-proBNP results (\>125pg/ml) an artificial intelligence (AI) echocardiogram and 12 lead electrocardiogram (ECG) will be performed at study site (within 28 days of NT-proBNP result). EHR will be reviewed at six months

Eligibility

Min Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a structured, team-based care program involving multiple specialists can identify heart failure earlier in people who are at high risk, before serious symptoms develop. **You may be eligible if...** - You are over 40 years old - You have at least two of the following risk factors for heart failure: coronary artery disease, Type 1 or 2 diabetes, atrial fibrillation, prior stroke, peripheral artery disease, chronic kidney disease, regular use of diuretics (water pills) for more than 30 days in the past year, COPD, obesity (BMI over 30), or current smoking **You may NOT be eligible if...** - You have already been diagnosed with heart failure - You have a very limited life expectancy or serious conditions that would make participation unsafe Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DIAGNOSTIC_TESTNT-proBNP

blood sample to measure N-terminal prohormone of B-type natriuretic peptide at local laboratory

DIAGNOSTIC_TESTAI echocardiogram

Artificial intelligence driven transthoracic echocardiogram

DIAGNOSTIC_TESTelectrocardiogram

tracing of electrical cardiac activity of the heart

OTHERCardiovascular physical examination

basic physiological measurements to include height (cm), weight (kg) and hip circumference (cm) and blood pressure (mmHg)

Locations(3)

Vancouver General Hospital

Vancouver, British Columbia, Canada

Montreal Heart Institute

Montreal, Quebec, Canada

University of Sherbrooke

Sherbrooke, Quebec, Canada

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05859048

Related Trials

Impact of Optimized Pacing Strategies on Clinical and Hemodynamic Outcomes in Heart Failure Patients With Pacemaker

NCT075631531 location

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

NCT06424288653 locations

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

NCT06935370638 locations

A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)

NCT06991257135 locations

HARMONY Trial : To Evaluate a Therapeutic and Monitoring Device(NOVAtria System) for Heart Failure Management

NCT074022391 location