RecruitingNCT05860400

Efficacy and Safety of Comprehensive Treatment in Patients With IR-CAD: a Self-controlled Cohort Study

Efficacy and Safety of Comprehensive Treatment in Patients With Inflammation-associated Rapidly-progressive Coronary Artery Disease (IR-CAD): a Self-controlled Cohort Study


Sponsor

Peking Union Medical College Hospital

Enrollment

39 participants

Start Date

May 17, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This is a self-controlled cohort study to evaluate the efficacy and safety of comprehensive treatment in patients with inflammation-associated rapidly-progressive coronary artery disease (IR-CAD) by comparing the study endpoints before treatment with those after treatment in the same group of patients.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Coronary revascularization, a behavioral approach called Healthy life style, and others for people with coronary artery disease, coronary artery disease progression, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALHealthy life style

Healthy diet, regular exercise, and quitting smoking

DRUGSecondary prevention for atherosclerotic coronary artery disease

Antiplatelet therapy, as well as medications for control of heart rate, blood pressure, low-density lipoprotein cholesterol, and blood glucose

DRUGImmunosuppressive therapy

Glucocorticoids and/or immunosuppressive agents

PROCEDURECoronary revascularization

Percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG).

DRUGSupportive therapies

Medical interventions for prevention and treatment of the side effects of the above treatment, such as abnormal liver function, hypocalcemia, hypokalemia, peptic ulcer, infection, et al.


Locations(1)

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China

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NCT05860400


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