RecruitingNot ApplicableNCT05868239

Impact of Aerosol Box Use During Cardiopulmonary Arrest: A Multicenter Study


Sponsor

KidSIM Simulation Program

Enrollment

240 participants

Start Date

Sep 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Aerosol Generating Medical Procedures (AGMP) are procedures that have the potential to create tiny particles suspended in the air. These particles can contain germs such as viruses. The Coronavirus Disease 2019 (COVID-19) pandemic was caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients infected with SARS-CoV-2 experience unusually high rates of critical illness that needs advanced airway management and intensive care unit admission. Bag-valve-mask (BVM) ventilation, endotracheal Intubation (ETI) and chest compressions are sometimes required for critically ill COVID-19 patients, and may contribute to a high risk of infection amongst Health Care Workers (HCW). To lessen HCW risk during high-risk procedures, a device called an aerosol box has been developed to place over the head of the patient, shielding the provider's face from virus droplets suspended in the air. The purpose of this research study is to better understand how particles disperse during AGMPs, more specifically during the provision of cardiopulmonary resuscitation (CPR). The project team hopes what is learned from the project can help inform infection control measures. This could help make changes to the clinical environment and make it safer for HCW's. The investigators intend to explore how an aerosol box performs in reducing contamination of HCW's who perform critical airway interventions during resuscitation events.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This multi-center simulation study investigates whether the use of aerosol boxes — protective enclosures placed over a patient's head during intubation — affects the quality of CPR and airway management during cardiac arrest. Aerosol boxes were widely adopted during the COVID-19 pandemic to protect healthcare workers from infectious droplets, but concerns arose that they might slow down or impair resuscitation efforts. This study uses simulated cardiac arrest scenarios to measure the actual impact on performance. Participants are healthcare providers — physicians, nurses, respiratory therapists, and others — with active life support certification who work in emergency medicine, pediatrics, or anesthesia. Eligible airway providers (intubators) must be attending physicians, fellows, or residents in relevant specialties with ACLS or PALS certification. Anyone who declines consent or cannot physically perform the required tasks is excluded. Participants are adults aged 18–60. Providers will complete simulated resuscitation scenarios with and without the aerosol box, with performance measured on metrics like time to intubation and CPR compression quality. This study matters because real-world cardiac arrest outcomes hinge on seconds — any barrier that impairs timely, effective resuscitation has life-or-death implications, and its true impact needs to be rigorously quantified.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEAerosol box

The aerosol box is a transparent, plastic cube covering the patient's head and shoulders, with circular access ports on the front of the box allowing for access to manage the airway. An additional four access holes (i.e. two on either side of the box) allow for airway assistants to access the patient airway.


Locations(4)

Department of Emergency Medicine, Children's Hospital of Los Angeles

Los Angeles, California, United States

KidSIM, Alberta Children's Hospital

Calgary, Alberta, Canada

Department of Pediatrics, The Hospital for Sick Children

Toronto, Ontario, Canada

Department of Pediatrics, CHU Sainte-Justine

Montreal, Quebec, Canada

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NCT05868239


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