The Effects of Exercise on Immune Phenotype of Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia Patients

This study looks at how exercise affects the immune system in people with slow-growing types of blood cancer, specifically indolent non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL). The goal is to understand if regular exercise can improve immune function in these patients. **You may be eligible if...** - You speak English and are between 18 and 80 years old - You have a confirmed diagnosis of indolent NHL or CLL/SLL - If currently on treatment, you have at least 8 weeks of treatment remaining - If post-treatment, you finished treatment at least 6 months ago with no more planned - If pre-treatment, you have no treatments scheduled during the 12-week study period **You may NOT be eligible if (healthy volunteers for Aim 1)...** - You have heart disease, COPD, asthma, or a physical limitation that prevents exercise - You are a current or former smoker **You may NOT be eligible if (lymphoma patients)...** - You have uncontrolled high blood pressure or heart problems - Your oncologist has not approved your participation Talk to your doctor to see if this trial is right for you.