A Study of DZD8586 Versus Investigator's Choice in r/r CLL/SLL (TAI-SHAN6)

This study (TAI-SHAN6) is comparing a new drug called DZD8586 against the doctor's choice of treatment in people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) — slow-growing blood cancers — that has relapsed (come back) or stopped responding to prior treatment. **You may be eligible if...** - You are 18 years or older - You have a confirmed diagnosis of CLL or SLL that has relapsed or is refractory - Your disease requires treatment - Your bone marrow and organ function are adequate - You are willing to follow contraceptive requirements during the study **You may NOT be eligible if...** - You have unresolved significant side effects from prior treatment - Your CLL/SLL has transformed into a more aggressive lymphoma (Richter transformation) - Your cancer has spread to the brain (CNS involvement) - You have major cardiovascular disease, active serious infection, or other uncontrolled conditions - You have swallowing difficulties or chronic gastrointestinal problems that would prevent taking oral medication Talk to your doctor to see if this trial is right for you.