RecruitingNot ApplicableNCT05879783

Optical Biopsy for Peritoneal Nodules in Colorectal Patients

Use of Probe-based Confocal Laser Endomicroscopy to Perform Optical Biopsy for Peritoneal Nodules in Colorectal Cancer Patients During Surgery

Sponsor

Nanfang Hospital, Southern Medical University

Enrollment

278 participants

Start Date

Sep 15, 2022

Study Type

INTERVENTIONAL

Conditions

Colorectal, Cancer

Summary

During surgery, peritoneal metastasis is typically confirmed pathologically through resection sample. However, this process can be time-consuming when utilizing intro-operative frozen section pathology. To address this issue, we propose utilizing confocal laser endomicroscopy to provide in situ, real-time, and in-vivo diagnosis of suspected peritoneal nodules as cancer metastasis during surgery.

Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study tests a technique called optical biopsy — using a special light-based probe during surgery — to identify whether small nodules found in the belly (peritoneal nodules) are cancerous in patients with colorectal cancer. The goal is to help surgeons determine what the nodules are without needing a traditional tissue biopsy. **You may be eligible if...** - You are between 18 and 85 years old - You have a diagnosis of colorectal cancer - You are about to have surgery for your cancer - You are in acceptable health for surgery (ASA class I, II, or III) **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have acute kidney failure or moderate to severe chronic kidney disease - You have severe liver damage - You have asthma or a known allergy to contrast agents Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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