Study of Bisoprolol (Nerkardou - Nerhadou International) 5 and 10 mg Oral Dissolvable Film (ODF) Treatment in Egyptian Patients With Essential Hypertension

This study tests bisoprolol — a heart rate-lowering blood pressure medication — in a new oral dissolving film (ODF) form in Egyptian patients with grade 1 or grade 2 high blood pressure who have not responded adequately to their current medication. The ODF form dissolves in the mouth and may be easier to take for some patients. **You may be eligible if...** - You are between 21 and 65 years old - You have newly diagnosed grade 1 or grade 2 hypertension (blood pressure between 140-179 mmHg systolic and/or 90-109 mmHg diastolic) - Your resting heart rate is 80 beats per minute or higher - You have not responded adequately to your current blood pressure medication and can safely switch to bisoprolol - Your BMI is between 18.5 and 30 **You may NOT be eligible if...** - Your blood pressure is in grade 3 (severely elevated, over 180/120 mmHg) - You have asthma or severe lung disease - You have diabetes, severe kidney or liver disease - You have a history of heart surgery or cardiovascular operations - You are pregnant or breastfeeding - You take certain medications that interact with bisoprolol Talk to your doctor to see if this trial is right for you.