Impact of Yo-Yo Sleep on Cardiometabolic Health
Columbia University
72 participants
Sep 22, 2023
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to test the impact of repeated intermittent short sleep, with short sleep maintained 5 days per week followed by 2 days of prolonged sleep, compared to daily adequate sleep, on energy balance and cardiometabolic risk. A secondary goal of this research is to determine if maintaining a constant midpoint of sleep while undergoing intermittent short sleep, leads to better outcomes than intermittent short sleep with a 2-hour delay in sleep midpoint. The aims of this research will be tested in the context of a 3-group, parallel-arm, outpatient intervention of 4 weeks in duration, in young-to-middle-aged adults (aged 18-49 years).
Eligibility
Inclusion Criteria3
- Aged 18 to 49 years
- BMI 20-29.9 kg/m2
- Habitually sleeping 7-9 hours/night without sleep aids or naps
Exclusion Criteria10
- Sleep disorders
- Psychiatric disorders (including eating disorders) and seasonal affective disorder
- Pregnancy (current/prior year)
- Breastfeeding
- Smokers (Any cigarette smoking or ex-smokers <3years)
- Diabetes
- Elevated blood pressure, taking beta-blockers
- Individuals taking anti-coagulants or anti-platelets
- Recent weight change or participation in a weight loss program or have ever had bariatric surgery or other weight loss or gastrointestinal procedure.
- Travel across time zones; shift work (non-traditional hours)
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Interventions
Restricted sleep duration of \<5.5 h/night for 5 nights (SR) followed by 2 nights of 9.5 hours of time in bed (TIB) (recover sleep) each week.
2-hour delayed sleep timing.
Goal of ≥7 hours of sleep/night with 8 hours of time in bed (TIB).
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05880758