RecruitingNCT05884008

Risk Evaluation by COronary CTA and Artificial intelliGence Based fuNctIonal analyZing tEchniques - I

Coronary Computed Tomography Angiography and Functional Analysis in Risk Stratification of Coronary Artery Disease: A Retrospective Cohort Study


Sponsor

Ruijin Hospital

Enrollment

300 participants

Start Date

May 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This study is a multicenter, retrospective imaging study. The study intends to retrospectively enroll patients with acute myocardial infarction who had received coronary CTA in a certain time-window before this event. All coronary CTA will be analyzed by anatomic, functional and radiomic analysis, assisted by artificial intelligence. The purpose of this study is to establish a coronary artery disease risk stratification system by coronary CTA.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria2

  • Age between 18-80 years old
  • Received coronary CT angiography 3 months to 5 years prior to acute coronary myocardial infarction. CCTA identified coronary atherosclerotic plaques with diameter stenosis ≥ 10%

Exclusion Criteria4

  • Familial hypercholesterolemia
  • Prior history of percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG)
  • Prior history of myocardial infarction before the recent event
  • Severe liver or renal insufficiency

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Locations(9)

Cangzhou Center Hospital

Cangzhou, Hebei, China

First affiliated hospital of Harbin Medical University

Harbin, Heilongjiang, China

First affiliated hospital of Zhengzhou University

Zhengzhou, Henan, China

Union Hospital, Tongji Medical College, Huazhong University of Science and Techonology

Wuhan, Hubei, China

First Hospital of Nanjing

Nanjing, Jiangsu, China

First affiliated hospital of Dalian Medical College

Dalian, Liaoning, China

General Hospital of Northern Theater Command

Shenyang, Liaoning, China

Ruijin Hospital, Shanghai Jiaotong University School of Medicine

Shanghai, Shanghai Municipality, China

Xinhua Hospital, Shanghai Jiaotong University School of Medicine

Shanghai, Shanghai Municipality, China

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NCT05884008


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