RecruitingNot ApplicableNCT05887284

Investigation of the Clinical Efficacy of Low-dose Ionizing Radiation in the Treatment of Osteoarthritis


Sponsor

University of Erlangen-Nürnberg Medical School

Enrollment

132 participants

Start Date

Jul 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

IMMO-LDRT02 is a prospective, placebo-controlled, double-blind, randomized trial to investigate the clinical efficacy of low dose radiation therapy (LDRT) in the treatment of arthrosis. Newly diagnosed or already existing arthroses of the fingers, wrists, shoulders, knees, ankles and feet will be enclosed. Finally, the evidence of clinical benefit from LDRT (6 x 0.5 Gy) will be compared to the placebo group (6 x 0 Gy), by determination via a visual analog scale and identification of immunological changes.


Eligibility

Min Age: 39 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying low dose radiotherapy (0.5 Gy), low dose radiotherapy (1.0 Gy), and others for people with arthrosis and osteoarthritis. The study is currently recruiting participants at 1 location. People eligible for this study include aged 39 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONlow dose radiotherapy (0.5 Gy)

12 times 0.5 Gy

RADIATIONmock radiation treatment

6 times 0.0 Gy

RADIATIONlow dose radiotherapy (1.0 Gy)

6 times 1.0 Gy


Locations(1)

Department of Radiation Oncology, Universitätsklinikum Erlangen

Erlangen, Bavaria, Germany

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NCT05887284


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