RecruitingNot ApplicableNCT05887674

Shanghai Non-pharmacological Intervention for Mild Cognitive Impairment and Mild Alzheimer's Disease

Shanghai Non-pharmacological Intervention for Mild Cognitive Impairment and Mild Alzheimer's Disease: Combined Low Inflammatory-index Diet, Physical Exercises, and Cognitive Training in Nursing Home


Sponsor

Ruijin Hospital

Enrollment

180 participants

Start Date

May 11, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This study is a multicentre, randomized, double-blind, controlled trial that aims to investigate the efficacy of multi-domain life-style intervention including low inflammatory-index diet, exercise, and cognitive training in patients with mild cognitive impairment and mild Alzheimer's disease.


Eligibility

Min Age: 60 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study is testing non-drug therapies — such as cognitive training, music therapy, or physical exercise — for people in Shanghai with mild cognitive impairment or mild Alzheimer's disease, to see if they can slow the progression of memory and thinking problems. **You may be eligible if...** - You are between 60 and 90 years old - You have been diagnosed with mild cognitive impairment or mild Alzheimer's disease according to standard criteria - You have a low depression score on the Hamilton scale (≤10) - You have at least a primary school education - You are able to give your own consent **You may NOT be eligible if...** - Your cognitive decline is caused by something other than Alzheimer's (such as stroke, infection, or Parkinson's disease) - You have serious heart, liver, or kidney disease - You are currently enrolled in another intervention study - You are not capable of completing cognitive assessments Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALDiet intervention

Low inflammatory-index diet

BEHAVIORALExercise

Guided muscle strength training and stretching exercises

BEHAVIORALCognitive training

Cognitive training will be implemented in person


Locations(1)

Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine

Shanghai, Shanghai Municipality, China

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NCT05887674


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