Combining Stellate Ganglion Block With Prolonged Exposure for PTSD
Combining Stellate Ganglion Block With Prolonged Exposure for PTSD: A Randomized Clinical Trial
The University of Texas Health Science Center at San Antonio
140 participants
Feb 26, 2024
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to compare the combination of Massed Prolonged Exposure (PE); a behavioral therapy for PTSD) and a stellate ganglion block (SGB; an injection of a local anesthetic into the front of the neck) with Massed Prolonged Exposure and a sham injection in a sample of military service members or retirees with PTSD. The main questions it aims to answer are: (1) Does the addition of an SGB improve treatment outcomes associated with Massed PE and (2) Do differences in psychophysiological arousal during the exposure portion of treatment help explain treatment outcomes for PTSD. Participants will receive ten 90-minute session of Massed PE. Between the first and second Massed PE sessions, half of the participants will receive a SGB, and half will receive a sham SGB.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
6.5cc of Ropivacaine hydrochloride (HCl) 0.5%, one time into the stellate ganglion
6.5cc of Normal Saline one time into the stellate ganglion.
Locations(2)
View Full Details on ClinicalTrials.gov
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NCT05889741