RecruitingNot ApplicableNCT05892042
Anti-CoagulaTion on Left Ventricular Thrombus After ST Segment Elevation Myocardial Infarction
Assessment of Anti-Coagulation Therapy on Patient With Left Ventricular Thrombus After ST Segment Elevation Myocardial Infarction
Sponsor
Jilin University
Enrollment
320 participants
Start Date
May 1, 2023
Study Type
INTERVENTIONAL
Conditions
Summary
Contemporary data are lacking regarding the management of left ventricular thrombus (LVT) developed after ST segment elevation myocardial infarction
Eligibility
Min Age: 18 YearsMax Age: 80 Years
Inclusion Criteria2
- Established ST segment elevation myocardial infarction within 7 days Left ventricular thrombus (LVT) is detected by either cardiac magnetic resonance (CMR) or TTE.
- Ongoing treatment with dual anti-platelet therapy according to ESC/AHA guidelines at the time of randomization
Exclusion Criteria2
- Clinically or hemodynamically unstable planed major surgeon such as CABG or Valve replacement within next 12 months Concomitant condition that requires anti- coagulation therapy, such as AF, DVT.
- Any contraindication of anticoagulant therapy History of intracranial hemorrhage; Woman who is currently pregnant, or breastfeeding serious impaired renal and liver functions life expectancy less than 1 year can not provide consent
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Interventions
DRUGRivaroxaban 15 MG [Xarelto]
Eligible subjects randomized into experimental group will receive rivaroxaban 15mg daily in addition to dual anti platelet therapy unless confirmed resolution of the left ventricular thrombus.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05892042
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