RecruitingNCT06963567

Left Ventricular Thrombus Registry

Observational Registry to Determine the Predictors and Outcomes of Patients at Risk of and Diagnosed With Left Ventricular Thrombus


Sponsor

Queen Mary University of London

Enrollment

1,500 participants

Start Date

May 17, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Left Ventricular Thrombus (LVT) is a blood clot that can develop in a poorly functioning heart. In around 1 in 6 patients who have had a heart attack or diagnosed with heart failure tend to develop blood clots in their main heart chamber. Having a blot clot in the main heart chamber can lead to serious complications such as stroke. Treatment for blood clots is blood thinning medications, which if taken for a prolonged period of time can result in bleeding which further complicates treatment. We hope to gather information to better understand the factors associated with blood clot formation and management in the lower left chamber of the heart. This understanding will hopefully enable us and others to improve management of this condition in the future and therefore help the wider population. As part of this study, bloods and scan results will be recorded and we will complete a short quality of life questionnaire. When participants come in for routine MRI scan, we may capture additional images for further research analysis. A sample of blood no more than one tablespoon will be collected for research analysis at the same time as routine blood test. This will occur at baseline and at around 6 months. At 12 months we will repeat the quality of life questionnaire and collect final data.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Patients with LV thrombus or;
  • Patients at risk for developing LV thrombus (e.g severe LV dysfunction, LV aneurysm, MI.

Exclusion Criteria2

  • Age < 18 years
  • Unable to consent

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Locations(1)

St Bartholomew's Hospital

London, United Kingdom

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NCT06963567


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